Zhou Changwen
professor
Department of Cell Biology and Genetics
Fujian Medical University
China
Biography
Zhou Changwen, male, born in June 1957 , doctor of science, professor, master tutor, 1982 Bachelor of Science degree in biology from Xinjiang University in 1991 , Master of Science in Biochemistry, Xinjiang Institute of Chemistry, Chinese Academy of Sciences in 1991 Degree, in 1999 in the Second Military Medical University, majoring in genetics doctorate degree. Professor of Department of Cell Biology and Genetics, School of Basic Medical Sciences, Fujian Medical University. Engaged in medical genetics, cell biology teaching and research work for more than 30 years, in the " androstenedione and bovine brucella monoclonal antibody preparation and application " , " Silk Road area thalassemia gene analysis and production Before diagnosis " , " preparation and identification of medical transgenic animal models " and " Alzheimer disease-related gene polymorphism analysis " and other fields have been studied in depth. In recent years, mainly engaged in "ADAM10 conditional knockout mouse model preparation and Alzheimer disease pathogenesis " research. Has presided over the military research project 2 , Fujian Province Natural Science Fund project 1 , Fujian Province, focus on the construction of university research projects1 , the level of scientific research projects 2 and jointly presided over the Fujian Provincial Experimental Animal Research Key Project 1 . In the "Journal of Genetics", "genetic" " GENE " and other domestic and foreign academic journals and conferences published more than 60 academic papers, SCI papers published several articles.
Research Interest
Disease genomics
Publications
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Zhou Changwen, Fu Jiliang, Xue Hong. Construction of p35 NCK5a gene repeat targeting vector and ES cell gene targeting study . Chinese Journal of Genetics , 2002; 27 ( 8 ): 659 - 665 .
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Liu Jun , Zhou Changwen (Corresponding author) , Wei Qiulan , Zhuang Jianlong , Zhao Linhua , Zheng Jiehui. Establishment and identification of mouse model of adult brain neuron specific ADAM10 knockout mice . Genetics , 2012 ; 34 (12): 1570-1576 .
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Zhuang Jianlong 1., QiulanWei, Lin Zhaohua, Changwen Zhou (Corresponding author) . Effects of ADAMlO ON Deletion of Notch Signaling. 1-pathwayand in neuronal Maintenance Adult Mouse Brain Gene,, 2015. ; 555 ( 2 ): 150-158.