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Jia Li

Professor
Department of Chemistry
Fuzhou University
China

Biography

Education: Degree (raise English) times the national professional institutions 1978.1-1982.7 China Fudan University School of Pharmacy, Bachelor of Pharmacy (BS) Masters (MS) 1984,9-1987,6 pharmacology China China Pharmaceutical University doctoral (PhD) 1990.1 -1993.11 SUNY pharmacology * * under the tutelage of the famous 1998 Nobel Prize winner Professor of Pharmacology Dr. Robert Furchgott work experience: 1982, 7-1984, 9 Fujian Province, China researcher at the Institute of Medical Science 1987, 7-1989,12 China Zhejiang Oriental Hospital Clinical Pharmacology Project Leader 1993, 12-1996,11 American Duke University Medical Center Postdoctoral fellow 1996,11-1998,7 American University of California School of Medicine senior researcher 1998,8-1999, 11 United States United States La Jolla drugs Senior researcher of the company Ⅲ 2000,3-2002,3 ​​Associate Professor, San Antonio Cancer Center, Texas, USA Deputy Director, Institute for Drug Development 20024- Present Senior Research Officer / Senior Pharmacologist, National Institute of Cancer Research, National Institutes of Health 2011-present China University of Fuzhou School of Chemistry and Chemical Engineering, National Thousand people plan

Research Interest

Cancer Pharmacy Dr. Li Li has been working on biomedical research and development for more than 20 years and has published more than 150 articles, including the International Journal of Natural Science (Science, Science, Proc. Natl. Acad. Sci. USA) and professional mainstream high impact factor academic journals (Pharmac; US; Nano Today; J. Phmarcol. Exp. Hard; Mol. Pharmacol .; J. Pharm. Sci. Br. J. Pharmacol .; Biochem. Pharmacol .; J. Med. Chem .; Curr Med. Chem.). I am often responsible for the work of the first author, the author of the communication or the main author. (Editor of the South African Medical Research Council), a consultant to the Science and Technology Group Publishers (USA), and 32 magazines for Drug Discovery Today. I have expertise in the field of innovative research and new drug development, research areas and directions related to anti-tumor drugs, anti-TB / AIDS drugs, cardiovascular drugs, nitric oxide (NO) biology, drug pharmacology and toxicity Medicine, herbal characteristics, drug analysis, absorption and distribution, metabolism and excretion (ADME), proteomics, and nano drugs. (Chair-elect) of the American Society of Pharmaceutical Design and Development (AAPS), familiar with the United States and China's new drug reporting procedures and management, author and published the Sino-US GLP Pharmacy policy and regulations, participated in 12 United States New drug declaration, and more than 30 new drug development projects. Invited to do academic reports> 32 times.

Publications

  • 2002 Effect of nanonization on absorption of 301029: Ex vivo and in vivo pharmacokinistic correlations determined by LC / MS. Total cited: 28; IF: 3.933 "Pharm. Res. 19: 1091-1096" 2003 Effect of Nitric Oxide on Cytotoxicity of Taxol: enhanced taxol transcellular domain. Total number of citations: 5; IF: 4.070 "Biochem. Pharmacol. 66 : 2193-2199" 2005 Pharmacodynamic and pharmacokinetic characteristics of SQ109, a new diamine-based antitubercular drug. : 5.204 "Br.J. Pharmacol. 144: 80-87"

  • 1996 S-nitrosohemoglobin: a dynamic activity of blood in in vascular control. Total citations: 1024; IF: 34.48 Nature. 380: 221-226 1996 Polynitrosylated proteins: characterization, bioactivity and functional consequences. Total citations: 135; IF: 9.432 Proc. Natl. Acad. Sci. USA 93: 4736-4741 1997 Blood flow regulation by S-nitrosohemoglobin in the physiological oxygen gradient. Total citations: 632; IF: 29.75 Science. 276: 2034-2037

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