Lin Zhonghui
Professor
Department of Chemistry
Fuzhou University
China
Biography
1999 - 2006 in Fujian Agriculture and Forestry University completed undergraduate and master's degree, received a master's degree. 2006 - 2009 in the Chinese Academy of Sciences Shanghai Institute of Drug Research Institute Shen Xu researcher engaged in anti-metabolic disease drug research, received a doctorate. 2009 - 2011 Postdoctoral research was conducted by Huang Mingdong, a researcher at the Institute of Material Structure of the Chinese Academy of Sciences. He is mainly engaged in the structural biology of urokinase and plasminogen activator inhibitor 1 (PAI-1) and the antithrombotic , Anti-tumor drug screening. November 2011 to March 2017 in the United States Howard Hughes Institute, the University of Texas Southwestern Medical Center Professor Yu Hongtao laboratory engaged in postdoctoral research, mainly engaged in mitotic process of key regulatory protein structure and function of the study, and to these proteins As a target for antitumor targeted drug research. Related research results published in Nature, Cell Chemical Biology, Structure, Biochemical Pharmacology and JBC and other magazines. Introduction to teaching
Research Interest
Structure and Function of Drug Target and Drug Design
Publications
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Zhonghui Lin, Longguang Jiang, Cai Yuan, Jan K.Jensen, Xu Zhang,et al.( 2011); Structural basis for recognition of urokinase-type plasminogen activator by plasminogen activator inhibitor-1. J. Biol. Chem., 286: 7027-32.
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Zhonghui Lin, Xuelian Luo, Hongtao Yu.(2016) Structural basis of cohesin cleavage by separase. Nature. 532: 131-134.
