Donghai Wu
Principal Investigator
Biomedicine and health
GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH
China
Biography
Dr.Wu received his B.Sc. in Biology from Beijing Normal University, China in 1984. He was then enrolled in the CUSBMEA program and went to University of Texas Southwestern Medical Center at Dallas where he obtained his Ph. D. in Biochemistry and Molecular Biology. Dr. Wu held faculty positions in the Department of Biochemistry, College of Medicine of University of Kentucky , the Department of Medicinal Chemistry, College of Pharmacy of University of Florida before he joined Guangzhou Institutes of Biomedicine and Health, Chinese Academy and Sciences in 2004. The major research interests and the long-term goal of his work are to understand the underlying molecular mechanisms of metabolic disorders such as diabetes and obesity, and to develop innovative biomedical strategies to promote the prevention, diagnosis and treatment of theses diseases. Dr. Wu has published more than 60 papers and held five patents.
Research Interest
Molecular mechanism of obesity related metabolic disorders,Stem cell biology and application in regenerative medicine, Large scale expression and production of commercially valuable proteins.
Publications
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Y Gao, YZhou, A Xu ,D Wu(2008) Effects of an AMP-activated protein kinase inhibitor, compound C, on adipogenic differentiation of 3T3-L1 cells Biol. Pharm Bull. 31: 1716-1722.
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KK Y Cheng, K S L Lam, YWang, C David, H Yu et al. (2007) Adiponectin-induced eNOS activation and Nitric Oxide Production are Mediated by APPL1 in Endothelial Cells Diabetes. 56: 1387-1394.
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YWang, JB Lam, KSL Lam, J Liu, MC Lam et al.(2006) Adiponectin Modulates the Glycogen Synthase Kinase-3B/B-Catenin Signaling Pathway and Attenuates Mammary Tumorigenesis of MDA-MB-231 Cells in Nude Mice. Cancer Res. 66: 11462 - 11470.
