Gao Zhonghong
Professor
chemical Engineering
Huazhong University of Science and Technology
China
Biography
Gao Zhonghong is the professor of Biological Inorganic Chemistry. His research interest focuses on the relationship between biological trace element iron and reactive oxygen species (ROS) & reactive nitrogen species (RNS). These researches including the study on the conditions of heme and heme-protein complexes catalized NO2--H2O2 nitrating protein tyrosine residues, identification of nitrated proteins in iron overload animal tissues and inhibitory effects of nature products and iron chelating agents. These researches will help to understand the molecular mechanisms of some diseases such as neurodegenerative disease, diabetes mellitus and liver injury. As a first author or corresponding author, he has published more than 30 papers in peer reviewed international journals such as PNAS, Free radic Biol Med, Chem Res Toxicol, etc, and these papers have got more than 700 citations. Gao teaches some courses such as Inorganic Chemistry, Inorganic Chemistry Experiments and General Chemistry for undergraduate students.
Research Interest
Chemistry & Chemical Engineering.
Publications
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4. Yuan C, Li H, Gao Z*. Amyloid beta modulated the selectivity of heme-catalyzed protein tyrosine nitration: an alternative mechanism for selective protein nitration. J Biol Inorg Chem. 2012, 17(7): 1083-1091
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3. Tu M, Abbood H., Zhu Z, Li H, Gao Z*. Investigation of the photocatalytic effect of zinc oxide nanoparticles in the presence of nitrite. J Hazard Matter. 2013, 244-245: 311-321.
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1. Huang Y, Shuai Y, Li H, Gao Z*. Tyrosine residues play an important role in heme detoxification by serum albumin. BBA- Gen. 2014, 1840(3):970-6
