Dawei Ma
Professor
Department of Chemistry
Institute of Organic Chemistry
China
Biography
Education and Appointments： 2000–present: Director, State Key Laboratory of Bioorganic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences 1995–present: Professor, State Key Laboratory of Bioorganic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, P. R. China 1990–1994: Postdoctoral fellow, University of Pittsburgh and Mayo Clinic, U.S.A. 1984-1989: Ph.D., Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences Major: Organic Chemistry Director: Prof. Xiyan Lu 1980-1984: B.S., Shandong University, Jinan, China Major: Chemistry
Research Interest
Total synthesis and SAR studies of complex natural products with interestin biological activates. Design, synthesis, and biological evaluation of selective modulators targeted GPCRs, kinases, proteases and apoptosis pathway. Development of new synthetic methodologies and their applications to synthesis of biologically and pharmaceutically important molecules.
Publications
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Qian Cai, Gang He and Dawei Ma*, Mild and Non-racemization conditions for Ullmann-type diaryl ether formation between aryl halides and tyrosine derivatives, J. Org. Chem. 2006, 71, 5268.
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Shouyun Yu, Xianhua Pan and Dawei Ma*, Total syntheses of halipeptins A-D, potent anti-inflammatory cyclic depsipeptides, Chem. Eur. J. 2006, 12, 6572.
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Dawei Ma*, Yongwen Jiang, Fangping, Chen, Li-kun, Gong, Ke Ding, Yong Xu, Renxiao Wang, Aihua Ge, Jin Ren*, Jingya Li, Jia Li and Qizhuang Ye, Selective inhibition of matrix metalloproteinase isozymes and in vivo protection against emphysema by substituted γ-keto carboxylic acids. J. Med. Chem. 2006, 49, 456.
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Qian Cai, Benli Zou, Dawei Ma*, Mild Ullmann-type biaryl ether formation reaction via combination of ortho-substituent and ligand effects, Angew. Chem. Int. Ed. 2006, 45, 1276.
