Tian-lu Cheng
Professor
Medicine
Kaohsiung Medical University
China
Biography
Dr. Tian-Lu Cheng received his Ph.D. from Academia Sinica and National Defense Medical Center. Currently, he is working as Professor in Kaohsiung Medical University. He is specialized in Humanized Antibody engineering, Functional molecular imaging, Tumor immunology and Functional genomics.
Research Interest
Antibody Engineering: Humanized Ab, Bispecific Ab, Pro-antibody; Functional Molecular Imaging; Tumor Immunology; Gene Therapy; Functional Genomics; Protein/antibody drugs
Publications
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Chuang CH, Wang WJ, Li CF, Ko CY, Chou YH, Chuu CP, Cheng TL, Wang JM. The combination of the prodrugs perforin-CEBPD and perforin-granzyme B efficiently enhances the activation of caspase signaling and kills prostate cancer. Cell death and disease. 2014 May;5:e1220.
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Su YC, Al-Qaisi TS, Tung HY, Cheng TL, Chuang KH, Chen BM, Roffler SR. Mimicking the germinal center reaction in hybridoma cells to isolate temperature-selective anti-PEG antibodies. MAbs. 2014 May;6(4):1069-1083.
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Chen YJ, Lin HC, Chen KC, Lin SR, Cheng TL, Chang LS. Taiwan cobra phospholipase A2 suppresses ERK-mediated ADAM17 maturation, thus reducing secreted TNF-α production in human leukemia U937 cells. Toxicon. 2014 May;86C:79-88.
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Cheng CM, Tzou SC, Zhuang YH, Huang CC, Kao CH, Liao KW, Cheng TC, Chuang CH, Hsieh YC, Tai MH, Cheng TL. Functional production of a soluble and secreted single-chain antibody by a bacterial secretion system. PLoS One. 2014 May;9(5):e97367.
