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Chemistry Experts

Tan Ninghua

Professor
State Key Laboratory of Phytochemisty
Kunming Institute of Botany
China

Biography

TAN Ninghua, Professor of phytochemistry. Major research interests include 1) chemistry and chemical biology of plant cyclopeptides: Discovery, structure, synthesis, biosynthesis, bioactivity, mechanism, evaluation for drug or probe; 2) chemistry, bioactivity and quality control of traditional Chinese medicines contained cyclopeptides; 3) e-Compound Library of Traditional Chinese Medicines (eCL-TCMs).

Research Interest

Phytochemistry

Publications

  • He WJ, Fu ZH, Zeng GZ, Zhang YM, Han HJ, Yan H, Ji CJ, Chu HB, Tan NH. Terpene and lignan glycosides from the twigs and leaves of an endangered conifer, Cathaya argyrophylla. Phytochemistry. 2012 Nov 30;83:63-9.

  • Leung HW, Wang Z, Yue GG, Zhao SM, Lee JK, Fung KP, Leung PC, Bik-San Lau C, Tan NH. Cyclopeptide RA-V inhibits cell adhesion and invasion in both estrogen receptor positive and negative breast cancer cells via PI3K/AKT and NF-κB signaling pathways. Biochimica et Biophysica Acta (BBA)-Molecular Cell Research. 2015 Aug 31;1853(8):1827-40.

  • Yue GG, Fan JT, Lee JK, Zeng GZ, Ho TW, Fung KP, Leung PC, Tan NH, Lau C. Cyclopeptide RA‐V inhibits angiogenesis by down‐regulating ERK1/2 phosphorylation in HUVEC and HMEC‐1 endothelial cells. British journal of pharmacology. 2011 Dec 1;164(7):1883-98.

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