Jing-fei Huang
Professor
State Key Laboratory of Genetic Resources and Evolution
Kunming Institute of Zoology
China
Biography
Jing-Fei Huang has done his PhD in Genetics. Currently he is working as Professor and Vice-Director in State Key Laboratory of Genetic Resources and Evolution in Kunming Institute of Zoology. Professor Jing-Fei Huang is the director of structural bioinformatics lab which focused on the relationship between protein sequence, structure and function. We apply Discovery Studio on drug design, virtual screening, and the specific binding type between protein-small molecule, protein-nucleic acid. We explore the evolution history of immune related gene and gene family through comparative genomics. We develop several method to research the relationship between protein structure variance and function diversity. We use system biology method to find candidate drug target in complex disease. Several papers of his work were published in reputed International journals.
Research Interest
Drug design, virtual screening, and the specific binding type between protein-small molecule, evolution history of immune related gene and gene family through comparative genomics,
Publications
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Chen S, Gao S, Cheng D, Huang J. The characterization and comparison of amyloidogenic segments and non-amyloidogenic segments shed light on amyloid formation. Biochemical and biophysical research communications. 2014 May 2;447(2):255-62.
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Cheng DQ, Li Y, Huang JF. Molecular evolution of the primate α-/θ-defensin multigene family. PloS one. 2014 May 12;9(5):e97425.
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Li GH, Huang JF. Inferring therapeutic targets from heterogeneous data: HKDC1 is a novel potential therapeutic target for cancer. Bioinformatics. 2013 Oct 24;30(6):748-52.
