Lu,changsheng
Associate Professor
Inorganic chemistry
Nanjing University
China
Biography
Dr. LU,Changsheng is an associate Professor in the Coordination Chemistry Institute (2005). He did PhD (1997-2000), MS (1995-1997), BS (1991-1995) of the Chemistry Department of Nanjing University. He completed his post-doc in Pharmacy College (UT Austin) from 2005 to 2007. His interest includes Coordination Chemistry, in the design and syntheses of the coordination complex polymers; Supramolecular Chemistry, in the cyclodextrins’ inclusion phenomena and cyclodextrin modification chemistry; Bio-inorganic Chemistry, in the design and expression of protein ligands for metal-based drugs; Chemical Biology, in the direct evolution of transpeptidase Sortase A.
Research Interest
Coordination Chemistry, Supramolecular Chemistry, Bio-inorganic Chemistry, Chemical Biology
Publications
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Lu Z, Lu C, Ren X, Meng Q. New metallocene-bridged cyclodextrin dimer: A stable derivative of the antitumor drug titanocene dichloride and its potent cytotoxity against human breast cancer (MCF-7) cells. Journal of organometallic chemistry. 2006 Dec 15;691(26):5895-9.
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Lu CS, Lu Z. A di (thio-1, 2-dicyane ethylenylthio) ethane-tethered β-cyclodextrin dimer as a molecular carrier of ferrocene in DMF solution. Journal of Inclusion Phenomena and Macrocyclic Chemistry. 2007 Dec 1;59(3-4):357-61.
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Zhu J, Lu C, Standland M, Lai E, Moreno GN, Umeda A, Jia X, Zhang Z. Single mutation on the surface of Staphylococcus aureus Sortase A can disrupt its dimerization. Biochemistry. 2008 Feb 12;47(6):1667-74.