Zuoren Yu
Professor
Biochemistry
Optimize Courier
China
Biography
Zuoren Yu is currently a Professor at Tongji University School of Medicine, Research Center for Translational, Shanghai East Hospital. After obtaining PhD degree in 2003 from Chinese Academy of Medical Sciences, he started Post-doctoral training at University of Pennsylvania School of Medicine and Thomas Jefferson University Kimmel Cancer Center. In 2009, he was assigned for a Faculty position in the track of Research Assistant Professor at Thomas Jefferson University. After joining Tongji University in Shanghai in 2012, he has been focusing on non-coding RNA regulation of breast cancer stem cells related with drug sensitivity, tumour regeneration and cancer metastasis. His main research work includes: Finding cell cycle regulator CCND1 is involved in the regulation of miRNA biogenesis and histone H3K9 tri-methylation, finding a regulatory loop between CCND1 and miR-17/20 in breast cancer, and demonstrating a microenvironment-mediated heterotypic signalling through which miR-17/20 regulate cross talking between cancer cells and inhibit breast cancer cell migration and metastasis.
Research Interest
DNA, RNA, Cancer
