Liu Xinyuan
Professor
Biochemistry and Cell Biology
Shanghai Institutes for Biological Sciences
China
Biography
LIU Xinyuan is a Professor of Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, hanghai, China. Research Areas: cancer(the most important keyword); super Interferon therapy; targeting gene-viroTherapy; oncolytic virus; gene therapy; targeting cancer stem cell therapy; organ specific cancer therapy Research Interests: Our major interest and our aim is to cure the cancer patients and also to control the viral disease especial the hepatitis B or C disease. It is possible because that we have a super interferon by which the therapeutic effect for hepatitis B in clinic has reached 62% and hope to be more higher, while the regular protocol for hepatitis B disease treatment is about 30%. For cancer therapy, super interferon has rescued many cancer patients. In experimental mice model, the targeting dual gene-virotherapy can eliminate all the xenograft tumor in many diverse cancers. Therefore it is possible for us to complete our aim.
Research Interest
Our major interest and our aim is to cure the cancer patients and also to control the viral disease especial the hepatitis B or C disease. It is possible because that we have a super interferon by which the therapeutic effect for hepatitis B in clinic has reached 62% and hope to be more higher, while the regular protocol for hepatitis B disease treatment is about 30%. For cancer therapy, super interferon has rescued many cancer patients. In experimental mice model, the targeting dual gene-virotherapy can eliminate all the xenograft tumor in many diverse cancers. Therefore it is possible for us to complete our aim.
Publications
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Wei-guo Zou, Chunxia Luo, Zilai Zhang, Jing Liu, Jingfa Gu, Zifei Pei, Cheng Qian,, Xin Yuan Liu (2004) A Novel Oncolytic Adenovirus Targeting to Telomerase Activity in Tumor Cells with Potent. Oncogene, 23(2): 457-464.
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Xin Yuan Liu, Songbo Qiu, Weiguo Zou, Zifei Pei, Jinfa Gu, Chunxia Luo, Hongmei Ruan, Yu Chen, Yipeng Qi* and Cheng Qian (2005) Effective Gene-Virotherapy for Complete Eradication of Tumor Mediated by the Combination of hTRAIL (TNFSF10) and Plasminogen k5. Mol. Therapy, 11(4): 531-541.
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Zi-fei Pei, Liang Chu, Weiguo Zou, Zilai Zhang, Songbo Qiu, Rong Qi, Jinfa Gu, Cheng Qian, Xin Yuan Liu (2004) Tumor Specific Targeting Adenovirus Mediates Smac to Augment the Antitumor Activity of TRAIL in Human Hepatoma. Hepatology, 39(5): 1371-1381.
