Tang Kun
Professor,Principal Investigator
Functional Human Genetic Variation
Shanghai Institutes for Biological Sciences
China
Biography
1996/9 - 2000/9: Jilin University, biochemistry, bachelor, Supervisor:Zhensan Piao 2001/1 - 2004/10: National University of Singapore, biochemistry, Ph. D. Supervisor: Prof. Dr. Carolin 2004/11-2007/12: MPI evolutionary anthropology, evolutionary genetic, postdoctoral, Supervisor:Prof. Dr. Mark Stoneking 2008/1-now: PICB,researcher/Principal Investigator
Research Interest
Our major research interest is to look for functional human genetic variations and to understand their biological mechanism and evolutionary roles. Genetically, People differ from each other by hundred thousands of small genetic variations. A small fraction of these genetic variations affect function. They make us a phenotypically very diverse species. Such phenotype diversity occurs among populations, such as skin pigmentation and lactose tolerance in adulthood etc.; and also between individuals, such as stature, weight, psychological tendency and drug metabolism. To understand these functional genetic variations, two strategies are to be applied. The first is to detect and characterize evidences of positive selection. The second strategy is to use association related approaches.
Publications
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Guo, Jianya(#),Mei, Xi,Tang, Kun(*) ,Automatic landmark annotation and dense correspondence registration for 3D human facial images.,BMC Bioinformatics,2013,14:232-232。EI,SCI,ISTP,SSCI
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Ging Guo(#) ,Jingze Tan(#) ,Yajun Yang,Hang Zhou,Sile Hu,Agu Hashan,Nurmamat Bahaxar,Shuhua Xu,Timothy D. Weaver,Li Jin,Mark Stoneking,Kun Tang(*) , Variation and signatures of selection on the human face,Journal of Human Evolution,2014, 75:143-152。EI,SCI,ISTP,SSCI
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Qian, Wei(#) ,Zhou, Hang,Tang, Kun(*),Recent coselection in human populations revealed by protein-protein interaction network., Genome Biology and Evolution,2015, 7(1):136-153。EI,SCI,ISTP,SSCI