Gaofeng Fan
Assistant Professor, PI
Life Science and Technology
Shanghai Tech University
China
Biography
1999.9 - 2003.7 B.Sc., Biology, Department of Intensive Institution, Nanjing University (Advisor: Dr. Genxi Li, Professor and Chair, Biochemistry). 2003.9 - 2009.7 Ph.D., Department of Biochemistry, Rutgers University-University of Medicine and Dentistry of New Jersey (Advisor: Dr. Céline Gélinas, Professor and Associate Dean). 2009.9 - 2017.2 Postdoctoral Fellow, Cold Spring Harbor Laboratory (Advisor: Dr. Nicholas K. Tonks, Professor and Deputy Director, FRS). 2017.2 – now Assistant Professor, PI, School of Life Science and Technology, ShanghaiTech University
Research Interest
Ovarian cancer metastasis and therapeutic resistance/Tyrosine phosphorylation/Poly-ADP Ribosylation
Publications
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Gaofeng Fan, Guang Lin, Robert Lucito and Nicholas K. Tonks. Protein-tyrosine Phosphatase 1B ÂAntagonized Signaling by Insulin-like Growth Factor-1 Receptor and kinase BRK/PTK6 in Ovarian Cancer Cells. Journal of Biological Chemistry (2013) 288(34): 24923-34 - Selected as “Paper of the weekâ€
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Gaofeng Fan*, Saadat Aleem*, Ming Yang, W. Todd Miller and Nicholas K. Tonks. Protein Tyrosine Phosphatase and Kinase Specificity in Regulation of SRC and BRK. Journal of Biological Chemistry (2015) 288 (34), 24923-24934 - Selected as “Paper of the weekâ€
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Gaofeng Fan*, Saadat Aleem*, Ming Yang, W. Todd Miller and Nicholas K. Tonks. Protein Tyrosine Phosphatase and Kinase Specificity in Regulation of SRC and BRK. Journal of Biological Chemistry (2015) 288 (34), 24923-24934 - Selected as “Paper of the weekâ€
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Gaofeng Fan, Siwei Zhang, Yan Gao, Peter A. Greer and and Nicholas K. Tonks. HGF-independent Regulation of MET and GAB1 by Non-Receptor Tyrosine Kinase FER Potentiates Metastasis in Ovarian Cancer. Genes & Development (2016) 30 (13), 1542-1557
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Prajwal Gurung*, Gaofeng Fan*, John R. Lukens, Peter Vogel, Nicholas K. Tonks and Thirumala-Devi Kanneganti. Tyrosine Kinase SYK licenses MyD88 Adaptor Protein to Instigate IL-1a-Mediated Inflammatory Disease. Immunity (2017) 46(4), 635-648 (*co-first author)
