Kurt Wüthrich
Distinguished Professor-in-Residence
iHuman Institute
Shanghai Tech University
China
Biography
1957–62 University of Bern, Switzerland: Lizentiat in chemistry, physics and mathematics. 1962–64 University of Basel, Switzerland: Ph.D. in chemistry (Prof. S. Fallab); Eidgen?ssisches Turnund Sportlehrerdiplom. 1964–65 University of Basel, Switzerland: Postdoctoral training (Prof. S. Fallab). 1965–67 University of California, Berkeley, CA, USA : Postdoctoral training (Prof. R.E. Connick). 1967–69 Bell Telephone Laboratories, Murray Hill, N.J., USA : Member Technical Staff, Biophysics Department (Dr. R.G. Shulman). 1969– ETH Zurich, Zurich, Switzerland: Privatdozent (70), Assistant Professor (72), Associate Professor (76), Professor of Biophysics (80); Chairman Biology Department (95–2000). 2001–04 The Scripps Research Institute, La Jolla, CA, USA: Cecil H. and Ida M. Green Visiting Professor of Structural Biology. 2004– The Scripps Research Institute, La Jolla, CA, USA: Cecil H. and Ida M. Green Professor of Structural Biology.
Research Interest
Biology, structure and function of proteins and nucleic acids; development of nuclear magnetic resonance (NMR) techniques for macromolecular structure determination in solution and for studies of intermolecular interactions; applications in structural genomics, proteomics and biomedical research.
Publications
-
Horst, R., Stanczak, P., Stevens, R.C. and Wüthrich, K. (2012) β2-adrenergic receptor solutions for structural biology analyzed with micro-scale NMR diffusion measurements. Angew. Chem. 52(1):331-335.
-
Stanczak, P., Zhang, Q., Horst, R., Serrano, P. and Wüthrich, K. (2012) Micro-coil NMR to monitor optimization of the reconstitution conditions for the integral membrane protein OmpW in detergent micelles. J. Biomol. NMR 54, 129–133.
-
Serrano, P., Pedrini, B., Mohanty, B., Geralt, M., Herrmann, T. and Wüthrich K. (2012) The J-UNIO protocol for automated protein structure determination by NMR in solution. J. Biomol. NMR 53, 341–354.
-
Horst, R., Stanczak, P., Serrano, P. and Wüthrich, K. (2012) Translational diffusion measurements by microcoil NMR in aqueous solutions of the Fos-10 detergent-solublized membrane protein OmpX. J. Phys. Chem. B 116, 6775–6780.
-
Liu, J.J., Horst, R., Katritch, V., Stevens, R.C. and Wüthrich, K. (2012) Biased signaling pathways in β2-adrenergic receptor characterized by 19F-NMR. Science 335, 1106-1110.
