Suwen Zhao
Assistant Professor, PI
Life Science and Technology
Shanghai Tech University
China
Biography
2004 B. En in Polymer Physics, University of Science and Technology of China, Hefei, China. Advisor: Qing-Xiang Guo 2009 Ph.D in Chemistry, Columbia University, New York, United States. Advisor: Richard A. Friesner 2010-2014 Postdoctoral Scholar, Department of Pharmaceutical Chemistry, University of California at San Francisco, San Francisco, United States. Advisor: Matthew P. Jacobson 2014-present Research Associate Professor, PI at iHuman Institute, Assistant Professor at School of Life Science and Technology, ShanghaiTech University, Shanghai, China
Research Interest
Predicting the full-length structures of multi-domain GPCRs Discovering ligands for GPCRs and other proteins in cell signaling pathways
Publications
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S. Zhao, K. Zhu, J. Li, R. A. Friesner, “Progress in super long loop predictionâ€, Proteins, 79, 2920-2935 (2011).
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R. Kumar, S. Zhao, A. Sakai, M. W. Vetting, B. M. Wood, S. C. Almo, J. V. Sweedler, J. A. Gerlt, J. E. Cronan, and M. P. Jacobson, “Prediction and biochemical demonstration of a catabolic pathway for the osmoprotectant, proline betaineâ€, mBio,5, (2014).
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M. P. Jacobson, C. Kalyanaraman, S. Zhao and B. Tian, “Leveraging structure for enzyme function prediction: methods, opportunities, and challengesâ€, Trends Biochem. Sci.,39(8), 363-71 (2014).
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S. Zhao, A. Sakai, X. Zhang, M. W. Vetting, R. Kumar, B. Hillerich, B. San Francisco, J. Solbiati, A. Steves, S. Brown, E. Akiva, A. Barber, R. D. Seidel, P. C. Babbitt, S. C. Almo, J. A. Gerlt and M. P. Jacobson, “Prediction and characterization of enzymatic activities guided by sequence similarity and genome neighborhood networksâ€, eLife, e03275 (2014).
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S. Zhao, R. Kumar, A. Sakai, M. W. Vetting, B. M. Wood, S. Brown, J. B. Bonanno, B. S. Hillerich, R. D. Seidel, P. C. Babbitt, S. C. Almo, J. V. Sweedler, J. A. Gerlt, J. E. Cronan, and M. P. Jacobson, “Discovery of new enzymes and metabolic pathways by using structure and genome contextâ€, Nature, 502, 698-702 (2013).
