Jason Joseph Chruma
Professor
College of Chemistry
Sichuan University
China
Biography
Jason Chruma was born and raised in the Phoenix Metropolitan Area of Arizona (USA) and earned his BS in Chemistry with Honors from the University of Arizona in 1997 working under the mentorship of Prof. Robin Polt. In 2002, he earned his PhD from the University of Pennsylvania studying under Prof. Amos B. Smith, III, and this was followed by an NIH post-doctoral fellowship at Columbia University from 2003-2005 with Prof. Ronald C. Breslow. He began his independent career as an Assistant Professor in the Department of Chemistry at the University of Virginia in 2005 before moving in August of 2012 to Sichuan University where he is now a Professor and Director of Doctoral Studies.
Research Interest
Prof. Chruma’s research interest focus on developing new methods for the synthesis of nitrogen-containing organic compounds and other biologically-active natural products involving such “green” methods as transition-metal catalyzed decarboxylative alkylations and intramolecular pericyclic reactions. The intent is to discover new molecular probes and tools to elucidate the biomolecular mechanisms involved in cellular differentiation and aniokis. Additional interests involve the design and synthesis of novel foldamer scaffolds and fluorescent linchpin reagents for bioconjugate synthesis.
Publications
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C. Fan, W. Wu, J. J. Chruma, J. Zhao, C. Yang* “Enhanced Triplet-Triplet Energy Transfer and Upconversion Fluorescence through Host-Guest Complexation†J. Am. Chem. Soc. 2016, 138(47), 15405-15412. [DOI:10.1021/jacs.6b07946] [SCI B, IF: 13.858]
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Z. Yan, Q. Huang, W. Liang, X. Yu, D. Zhou, W. Wu, J. J. Chruma, C. Yang* “Enantiodifferentiation in the Photoisomerization of (Z,Z)-1,3-Cyclooctadiene in the Cavity of g-Cyclodextrin─Curcubit[6]uril-Wheeled [4]Rotaxanes with an Encapsulated Photosensitizer†Org. Lett. 2017, 19(4), 898-901. [DOI:10.1021/acs.orglett.7b00057] [SCI C, IF: 6.579]
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J. Yao, W. Wu, W. Liang, D. Zhou, J. J. Chruma, G. Fukuhara, T. Mori, Y. Inoue, C. Yang* “Temperature-Driven Planar Chirality Switching of a Pillar[5]arene-based Molecular Universal Joint†Angew. Chem. Int. Ed. 2017, 56(24), 6869-6873. [DOI: 10.1002/anie.201702542] [SCI B, IF:11.994]
