He Jiankui
Associate Professor
Biology
South University of Science and Technology of China
China
Biography
He Jiakui, the national "thousands of people plan" specialists. He Jiankui has a multidisciplinary background, and in the gene sequencer research, CRISPR gene editing, bioinformatics and other fields to achieve research breakthroughs. Dr. He Jiankui team developed a third-generation single-molecule gene sequencer for Asia's first independent intellectual property in 2015, and its results were reported by Nature Biotechnology. Dr. He Jiankui published many papers in the world's top academic journals such as Science Translation Medicine, Physics Review Letters. Dr. He Jiankui presided over the National Science and Technology Key Research Program focused on a special subject, presided over the National Natural Science Fund Project 2. Dr. He Jiankui focus on industrial transformation, founded the Shenzhen Hanhai gene biotechnology Limited.
Research Interest
CRISPR-Cas9 gene editing In recent years, in the development of single-cell genome-wide sequencing method to detect CRISPR-Cas9 gene editing off target effect, for gene editing in clinical application laid an important foundation. Bioinformatics and genomics New techniques for single cell sequencing, including single chromosome sequencing, single cell DNA / RNA integration, genome sequencing, etc. Single molecule DNA and protein sequencing technology Single-molecular sequencing technology without amplification, and the development of large-scale parallel protein sequencing technology
Publications
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He J, Deem M, (2010) Heterogeneous Diversity of Spacers within CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats). Phys Rev Lett 105: 128102.
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Luwen N, Geng L, Guibo L, Yong H, He J, et al. (2014) Current Challenges in the Bioinformatics of Single Cell Genomics. Frontier in Oncology 4: 74.
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Luwen N, Zhoufang Li, Heng-Ye M, Pinghua L, He J, et al. (2015) Whole-Cell of SINGLE Assessment Genome Amplification Methods for Detecting the using hippocampal neurons & Copy Number Variation. Scientific Reports 5: 11415.