Kah-leong Lim
Visiting Professor
Institute of Advanced Materials
The Institute of Advanced Materials
China
Biography
Biographical Information 1999: PhD, Singapore Institute of Molecular & Cell Biology 2000-2001: Post Doc., Department of Pathology in Harvard Medical School 2001-2002: Post Doc., Department of Neurology in Johns Hopkins University School of Medicine
Research Interest
Research Interests: - Pathogenic mechanisms underlying neurodegeneration in Parkinson’s disease (PD) - Genetic fly and mouse models of PD - Relationship between PD and cancer
Publications
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3. Ng, C.H., Mok, Z.X.S., Koh, C., Ouyang, X., Fivaz, M.L., Tan, E.K., Dawson, V.L., Dawson T.M., Yu, F., and Lim, K.L. (2009) Parkin Protects Against LRRK2 G2019S Mutant-induced Dopaminergic Neurodegeneration in Drosophila Journal of Neuroscience, 29, 11257-11262
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2. Lee, JY, Nagano, Y, Taylor, J.P, Lim, K.L., Yao, TP (2010) Disease-causing mutations in Parkin impair mitochondrial ubiquitination, aggregation and HDAC6-dependent mitophagy. Journal of Cell Biology, 189, 671-9
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1. Lim, K.L. and Lim, G.G (2011) K63-linked ubiquitination and neurodegeneration. Neurobiology of Disease 43, 9-16
