Prof. Chen Xiaoyuan
Senior Investigator
Institute of Advanced Materials
The Institute of Advanced Materials
China
Biography
Biographical Information 1993: Bachelor, Department of Chemistry, Nanjing University 1996: MS, Department of Chemistry, Nanjing University 1999: PhD, University of Idaho 1999-2001: Post Doc., Syracuse University and Washington University respectively 2002-2004: Assistant Professor, University of Southern California 2004-2007: Molecular Imaging Program at Stanford 2008-2009: Associate Professor, Molecular Imaging Program at Stanford 2009-present: Senior Investigator and Lab Chief, National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Research Interest
Research Interests: LOMIN specializes in synthesizing molecular imaging probes for positron emission tomography (PET), single-photon emission computed tomography (SPECT), magnetic resonance imaging (MRI), optical (bioluminescence, fluorescence and Raman), contrast enhanced ultrasound, photoacoustic imaging, as well as multimodality imaging. This research group aims to develop molecular imaging toolbox for better understanding of biology, early diagnosis of disease, monitoring therapy response, and guiding drug discovery/development. LOMIN puts special emphasis on high-sensitivity nanosensors for biomarker detection and theranostic nanomedicine for imaging, gene and drug delivery, and monitoring of treatment. Research interests and ongoing projects include: - Ultrasensitive methods for multiplexed biomarker detection - Construction of nanoparticle platforms for effective drug and gene delivery - Probe synthesis for multimodality whole-body imaging of both extracellular and intracellular events - Clinical translation of molecular imaging probes targeting important biological processes - "All-in-one" theranostics for detection and monitoring of diseases as well as delivery of therapeutics
Publications
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3. Zhang P, Liu G, Chen X. Nanobiotechnology: Cell membrane-based delivery systems[J]. Nano Today, 2017, 13: 7-9.
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2. Liu Y, Wang S, Ma Y, et al. Ratiometric Photoacoustic Molecular Imaging for Methylmercury Detection in Living Subjects[J]. Advanced Materials, 2017, 29(17).
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1. Chen G, Qiu H, Prasad P N, et al. Upconversion nanoparticles: design, nanochemistry, and applications in theranostics[J]. Chemical reviews, 2014, 114(10): 5161-5214.