Prof. Zhang Cheng-wu
Professor
Institute of Advanced Materials
The Institute of Advanced Materials
China
Biography
Biographical Information 1998-2003: PhD degree in Physiology, Sichuan University, Sichuan China. 2003-2005: Post-Doc, Shantou Medical College, Shantou University. 2005-2009: Research Scientist, Singapore General Hospital, Singapore. 2009-2015: Senior Research Scientist, National Neuroscience Institute of Singapore. 2015-- : Professor; Institute of Advanced Materials, Nanjing Tech University. Academic Achievements Prof. ZHANG Cheng-Wu's research interest focuses on investigating the underlying mechanisms of Parkinson's disease with series of in vitro and in vivo models including primary cells, drosophila, mouse and human derived iPS. In recent years, he takes advantage of Biochemistry and Nanotechnology to develop novel diagnostic and therapeutic strategy for Parkinson's disease. He has chaired and completed one Singhealth Research Grant and one NMRC grant of Singapore. He published more than ten peer reviewed international papers including Nature Commnuications, Angewandte Chemie-International Edition, Stem Cells, Neurodegenerative Diseases, Frontiers in Aging Neuroscience, Investigative Ophthalmology &Visual Science, ect.
Research Interest
Research Interests 1. Utilizing cells, drosophila, mouse, as well as human derived induced pluripotent stem cells (iPS) as models to investigate the cellular and molecular mechanisms underlying pathogenesis of Parkinson's disease. 2. Taking advantage of Biochemistry and Nanotechnology to develop novel diagnostic and therapeutic strategy for Parkinson's disease.
Publications
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3. Lin Li, Cheng-Wu Zhang, Jing-yan Ge, Linghui Qian, Bing-Han Chai, Qing Zhu, Jun-Seok Lee, Kah-Leong Lim, and Shao-Qin Yao. (2015) A Small-Molecular Probe for Selective Profiling and Imaging Monoamine Oxidase B Activities in Models of Parkinson's Disease. Angew. Chem. Int. Ed, 54, 10821-10825 (Co-first author)
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2. Cheng-Wu Zhang, Henry Basil Adeline, Bing-Han Chai, Eugenia T.E. Hong, Chee-Hoe Ng, Kah-Leong Lim. (2016) Pharmacological or genetic activation of Hsp70 protects against loss of parkin function. Neurodegenerative Diseases, 16 (Co-corresponding author)
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1. Cheng-Wu Zhang, Liting Hang, Tso-Pang Yao and Kah-Leong Lim. (2016) Parkin Regulation and Neurodegenerative Disorders. Frontiers in Aging Neuroscience, 7(article 248): 1-15
