Jose C. Pastor-pareja
Professor
Cell Biology，Developmental Biology and Genetics
Tsinghua University
China
Biography
Jose C. PASTOR-PAREJA is an Associate Professor in Department of Cell Biology，Developmental Biology and Genetics at Tsinghua University, China. Jose C. PASTOR-PAREJA is an Associate Professor in Department of Cell Biology，Developmental Biology and Genetics at Tsinghua University, China.
Research Interest
One of the main barriers to our understanding of living organisms is complexity at the level of tissues. Basement membranes (BMs), which support tissues in all animals, are polymers of highly conserved extracellular matrix proteins. BMs and their components play essential roles in morphogenesis, cell signaling, immune responses, regeneration and tumor progression. I have recently shown that Collagen IV and Perlecan, two of the main components of BMs, exert opposing physical forces that determine cell and organ shape. Several undergoing projects in my laboratory investigate the secretion of BM components, their assembly into a polymer and their roles in development, regeneration and cancer.
