William E. Balch
professor
Department of Immunology and Microbiology
Tsinghua University
China
Biography
Professor Department of Molecular Medicine California Campus Laboratory Website Scripps VIVO Scientific Profile webalch@scripps.edu (858) 784-2310
Research Interest
Our laboratory is interested in understanding the rules that direct protein traffic through secretory pathway of eukaryotic cells. We use structural, biochemical, morphological and molecular tools to study mechanisms of protein folding and protein-protein interactions that mediate membrane vesicle targeting and fusion. We are particularly interested in defining the key trafficking defects that lead to hereditary amyloid disease, childhood emphysema, and cystic fibrosis, all diseases related to the inability of specific proteins to be properly transported to their site of function in the cell.
