Yong-bin Yan

Biography

Yong-Bin Yan is a Professor in Department of Biophysics, Biochemistry and Molecular Biology at Tsinghua University, China. Yong-Bin Yan is a Professor in Department of Biophysics, Biochemistry and Molecular Biology at Tsinghua University, China.

Research Interest

We are studying the structure, components, folding, assembly, physiological and pathological roles of cellular bodies including aggresomes/inclusion bodies and RNA granules via biophysical, biochemical and cellular methods. The present projects are; 1. Protein aggregation in conformational diseases: protein folding, misfolding and aggregation by biospectroscopy, particular of aggregation in inherited eye diseases and pathological conditions; 2. Ribonucleases and mRNA decay: structure and function of ribonucleases and their role in the regulation of mRNA turnover, with a focus on deadenylases. We are also interested in the structural basis of assembly and physiological functions of various RNA granules; 3. Creatine kinase and intracellular energy homeostasis: mechanisms of intracellular energy homeostasis regulated by creatine kinase and its binding partners.