Zheng

Biography

2016-Now, Researcher, School of Medicine, Tsinghua University 2014-2016, Associate Professor, Department of Molecular Biology, Princeton University  2014, Gallo Outstanding Science Award, New Jersey Cancer Research Council 2011-2014, Postdoctoral Foundation, Susan Komen Breast Cancer Foundation 2010-2014, Postdoc, Department of Molecular Biology, Princeton University  2005-2010, PhD, Cytology and Cancer Center, Albany School of Medicine 1999-2003, undergraduate, Department of Biological Sciences, Nanjing University

Research Interest

Cancer is a worldwide human health threat. In China, the incidence of cancer is rapidly rising in recent years. When the tumor incidence in situ, the cure rate and survival probability of patients is very high, but when the spread of tumor cells to other body tissues and organs when the key (cancer metastasis), the patient's survival is expected to be greatly reduced. Cancer cells that metastasize to other tissues are often less sensitive to traditional chemotherapy or radiation therapy. Recent studies have found that the tumor microenvironment (tumor surrounding normal tissue structure and tissue cells) have a great effect on metastasis and resistance of cancer. The use of advanced mouse models, bioinformatics analysis, and traditional cellular and molecular biology, I would go to the laboratory revealed a tumor cell - cell interactions important function of tissues in cancer metastasis and drug resistance of. These new discoveries can help us design more effective cancer treatments to inhibit cancer metastasis and reduce cancer resistance. 1. NOTCH signaling pathway in the occurrence and metastasis of breast cancer function 2. Functions of the ubiquitinated protein degradation pathway in carcinogenesis and metastasis 3. Tumor cell - tissue cell interactions in tumor metastasis and tumor resistance in the function