Tu Xiaoming
Professor
School of Life Sciences
University of Science and Technology of China
China
Biography
Dr. TU Xiaoming is an associate professor and member of New Century Excellent Talent Program of Ministry of Education. From 1993 to 2002, he studied in the School of Life Science, USTC, and earned his bachelor's, master's and doctoral degree successively. From August 2002 to July 2005 he did his postdoctoral research at the University of California at San Francisco. In July 2005 Dr. Tu returned to USTC as an outstanding scholar. Dr. Tu has published 22 papers including those with him as the first or corresponding author in Molecular Biology of the Cell, Journal of Cell Science, and Journal of Biological Chemistry.
Research Interest
We are attempting to study the structure and function of a number of proteins involved in a variety of cellular events. Currently, we are focusing on elucidation of the structure, function and their relationship of ubiquitin-like family proteins from eukaryote, prokaryote and archaea. We are also attempting to elucidate the molecular mechanism of cell cycle regulation and gene expression regulation in Trypanosoma brucei. We are currently focusing on the two PWWP domain containing proteins involved in the gene expression regulation.
Publications
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Shanhui Liao, Tao Wang, Kai Fan and Xiaoming Tu (2010) The small ubiquitin like modifier is essential in regulating mitosis in Trypanosoma brucei. Experimental Cell Research. 316: 704-715.
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Wen Zhang, Jiahai Zhang, Xuecheng Zhang, Chao Xu and Xiaoming Tu (2011) Solution structure of Taf14 YEATS domain and its roles in cell growth of Saccharomyces cerevisiae. Biochemical Journal. 436: 83-90.
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Kun Dai, Shanhui Liao, Jiahai Zhang, Xuecheng Zhang and Xiaoming Tu (2011) Solution structure of tensin2 SH2 domain and its phosphotyrosine-independent interaction with DLC-1. PLoS ONE. In press.
