Xiao Weihua
Professor
Life Sciences
University of Science and Technology of China
China
Biography
Dr. Xiao received his B.S and PhD. in Medicine from Norman Bethune University, Changchun China, and M.S. in Bioinformatics from Johon Hopkins University, Maryland USA. He was an research associate at Changchun Institute of Biological Products, Changchun, China from 1985 to 1995. He was a postdoctoral fellow under the guidance of Dr. Dhan Kalvakolanu in Cancer Canter at University of Maryland from 1995 to 1998. During 1998-2005, he worked as a scientist at National Cancer Institute, NIH, USA. In the later of 2004, he became a Principle Investigator at Institute of Immunology and School of Life Science in University of Science & Technology of China, and appointed as executive director of the program of medicinal biotechnology and director of GMP Laboratory of Medicinal biotechnology.
Research Interest
Signaling transduction and transcription in cancer and immune cells; Inflammation and Cancer Immunity; Medicinal Biotechnology.Development of Biological drugs;Development of Immune cell therapy.
Publications
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Ren Z, Kang W, Wang L, Sun B, Ma J, Zheng C, Sun J, Tian Z, Yang X, Xiao W. E2F1 renders prostate cancer cell resistant to ICAM-1 mediated antitumor immunity by NF-κB modulation. Mol Cancer. 2014 Apr 17;13:84.
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Zhong Y, Yang L, Guo Y, Fang F, Wang D, Li R, Jiang M, Kang W, Ma J, Sun J, Xiao W.High-temperature cultivation of recombinant Pichia pastoris increases endoplasmic reticulum stress and decreases production of human interleukin-10. Microb Cell Fact. 2014 Nov 26;13:163. doi: 10.1186/s12934-014-0163-7.
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.Guo Y, Wu J, Jia H, Chen W, Shao C, Zhao L, Ma J, Li R, Zhong Y, Fang F, Wang D, Sun J, Qian F, Dai X, Zhang G, Tian Z, Xiaoyi Li B, Xiao W. Balancing the Expression and Production of a Heterodimeric Protein: Recombinant Agkisacutacin as a Novel Antithrombotic Drug Candidate. Sci Rep. 2015 Jul 6;5:11730.
