Zhou Rongbin
Professor
School of Life Sciences
University of Science and Technology of China
China
Biography
HOU Rongbin is a professor and doctoral supervisor, selected into the Hundred Talents Program of CAS.He received his BSc. In 2002 and PhD. In 2007 from University of Science and Technology of China. Dr. Zhou did his postdoc research in University of Lausanne in Switzerland from 2007 to 2011. His papers are mainly published in journals such as Nature, Science，Nat Immunol，PNAS，J IMMUNOL and Hepatology. He was the recipient of the CAS President Special Award in 2007 and the CAS Prize for Outstanding Doctoral Dissertation in 2008.In 2012 his project won the support of the first 'Outstanding Youth Science Fund Project' under the National Natural Science Foundation of China.
Research Interest
Our general interest is to understand how pathogen and danger signal trigger innate immunity and inflammation, and includes the following areas: 1.Molecular mechanisms of innate immune recognition and signal transduction: Analysis of the receptors (pattern recognition receptors, PRRs) the involved in innate immune recognition, including identification of new activators and clarification of the signaling transduction pathways. Our particular interest is to understand the signaling networks that control the activation of “inflmmaosme”. 2.Basic biology of inflammation: Inflammation is a fundamental biological response to harmful stimuli, such as pathogens and danger. We are studying the signaling networks that control the initiation, progression and termination of inflammatory responses. We also have interest to understand the links between inflammation and metabolism disorder, inflammation and cancer.
Publications
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Huang Z, Wu SQ, Liang Y, Zhou X, Chen W, Li L, Wu J, Zhuang Q, Chen C, Li J, Zhong CQ, Xia W, Zhou R, Zheng C, Han J. RIP1/RIP3 Binding to HSV-1 ICP6 Initiates Necroptosis to Restrict Virus Propagation in Mice. Cell Host Microbe. 2015;17(2):229-42.
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Wang X, Jiang W, Yan Y, Gong T, Han J, Tian Z*, Zhou R*. RNA viruses promote activation of the NLRP3 inflammasome through a RIP1-RIP3-DRP1 signaling pathway. Nat Immunol. 2014 ;15(12):1126-33.
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Yan Y, Jiang W, Liu L, Wang X, Ding C, Tian Z*, Zhou R*. Dopamine controls systemic inflammation through inhibition of NLRP3 inflammasome. Cell. 2015 ;160(1-2):62-73.
