Department of Biological Sciences
Cyprus University of Technology
980 - 1984 Predoctoral Fellow, Department of Biochemistry, Medical College of Ohio, Toledo, Ohio 1984 - 1986 Postdoctoral Fellow, Department of Molecular Biology, Northwestern University Medical School, Chicago, Illinois 1986 - 1990 Postdoctoral Appointee, Division of Biological and Medical Research, Argonne National Laboratory, Argonne, Illinois 1990 - 1992 Research Biologist, IIT Research Institute, Chicago, Illinois 1992 - 1994 Assistant Professor, Specialized Cancer Center and Department of Genetics, School of Medicine, University of Illinois at Chicago, Chicago, Illinois 1994 - 1997 Assistant Professor, Department of Surgical Oncology and Department of Genetics, University of Illinois at Chicago, Chicago, Illinois 1997 - 2002 Associate Professor, Department of Surgical Oncology, Department of Genetics and Department of Pharmacology, University of Illinois at Chicago, Chicago, Illinois 2000 - 2002 Associate Professor, Medicinal Chemistry/Pharmacognosy, College of Pharmacy University of Illinois at Chicago, Chicago, Illinois 2000 - 2002 Director of Research, Functional Foods for Health (FFH) Program 2004 - 2006 Chairman, Department of Biological Sciences, University of Cyprus 2006 - 2008 Dean, Faculty of Pure and Applied Sciences, University of Cyprus 2009 - 2012 Chairman, Department of Biological Sciences, University of Cyprus 2002 - present Professor of Molecular Biology, University of Cyprus. 1997 – present Associate Editor for Nutrition and Cancer, an International Journal 2002 – present Member, Editorial Board, in vivo.
Role of nutrition in carcinogenesis; cancer chemoprevention. Interactions between botanicals and drugs; especially tamoxifen and soy phytoestrogens. Molecular targets of antitumor drugs, especially DNA-topoisomerases. Phytoestrogens and Selective Estrogen Receptor Modulators (SERMs). Cancer epigenetics and targetted therapeutics.
Pitta C, Papagiorges P., Constantinou AI. Combination treatment with TSA and 5-aza-dc restores response to tamoxifen in tamoxifen resistant ER-β negative breast cancer cells. Cancer Lett. 337: 167-176, 2013
retu E, Karonen M, Salminen JP, Mircea C, Constantinou AI,et al. In vitro study of the antioxidant activity of a polyphenol-rich extract from Pinus brutia bark and its fractions. J Med Food16:984-91, 2013
Miron A, Olymbiou C, Charalambous C, Neophytou C,Constantinou AI et al. Chemical composition, antioxidant and antiproliferative activity of a polyphenol-rich fraction from Pinus sylvestris L. Bark.