Department of Biological Sciences
Cyprus University of Technology
Assistant Professor (2010 onwards) - Biological Sciences at University of Cyprus Postdoctoral researcher (2004-2009) - Chromatin and Epigenetics at University of Cambridge, UK PhD (1999-2004) - Cellular and Molecular Biology at University of Wisconsin-Madison, USA B.A. (1995-1999) - Biology at Lawrence University, USA
The overall aim of our group is to understand how epigenetic mechanisms, such as those involving histone modifications, control the transcription of genes. We are driven by the fact that deregulation of these mechanisms leads to diseases such as cancer. To accomplish the above research aim we employ interdisciplinary approaches including molecular biology, biochemical, genetic, genomic and proteomic techniques using both mammalian and yeast cells as model systems. For more information please visit our lab website at http://www.kirmizislab.com Current Lab Members Christina Demetriadou - PhD student (cdemet92[at]gmail.com) Dimitris Kyriakou - PhD Student (dimitris-kyriakou[at]hotmail.com) Ioanna Antoniou - Undergraduate thesis student (antoniou.ioanna[at]ucy.ac.cy) Tonia Konstantinou - Undergraduate thesis student (konstantinou.tonia[at]ucy.ac.cy) Previous Lab Members Christis Demosthenous Diego Molina Serrano Nayia Nicolaou Demetria Pavlou Manolis Stavrou Vassia Schiza Aaron Plys
Kyriakou, D. et al. Functional characterisation of long intergenic non-coding RNAs through genetic interaction profiling in Saccharomyces cerevisiae. BMC Biology 14(1):106 (2016).
Molina-Serrano, D. et al. Loss of Nat4 and its associated histone H4 N-terminal acetylation mediates calorie restriction-induced longevity. EMBO Rep 17(12):1829-1843 (2016).
Molina-Serrano, D & Kirmizis, A. Calorie restriction breaks an epigenetic barrier to longevity. Cell Cycle 20:1-2 (2017).