Department of Biological Sciences
Cyprus University of Technology
ducation B.S. 1994 Biology, University of Crete, Greece M.S. 1996 Molecular Genetics, University of Crete, Greece Ph.D. 2001 Molecular Genetics, University of Crete, Greece - academic positions 2012- Assistant Professor, Department of Biological Sciences, University of Cyprus 2008-12 Instructor, Harvard Medical School, Boston, USA 2008-12 Assistant in Biology, Massachusetts General Hospital, USA 2008-12 Research Staff, Shriners Hospital for Children, Boston,USA 2002-08 Postdoctoral Fellow, Harvard Medical School, USA - web research profiles ResearchGate FrontiersIn-Loop PubMed F1000
Modeling of human infectious diseases and carcinogenesis in Drosophila and mouse (click for more) Our goal is to establish synergisms among gene allelles, microbes and the intestinal environment that predispose for intestinal inflammation and cancer. The work of our team aims towards a deeper understanding of critical aspects of intestinal human disease, including inflammatory bowel disease and intestinal tumor formation and metastasis. We use Drosophila genetics, histopathology and quantitative population genetics analysis to identify the host genes, microbes and dietary factors that mediate inflammation and predispose for cancer. We model human diseases primarily in flies, subsequently in mice and we follow up with human studies based on the high degree of conservation between Drosophila and mammalian signalling pathways controlling intestinal inflammation and cancer. Key Funding & Licensing Biomarker assessment in Fecal, Blood and Colon Biopsy samples for improved diagnosis and prognosis of Colon Cancer in the Cypriot Population National Bioethics Committee (Nicosia, Cyprus) 2016-07 | Licenced to YA and colleagues Protocol number: EEBK/ΕΠ/2015/38 Dietary and pharmacological intervention for preventing intestinal tumorigenesis Fondation Sante (Athens, Greece) 2017-03 to 2019-2 | Grant to YA Grant number: YA-Sante2 Bacterial interactions that establish a low inflammatory state in the Drosophila and mouse intestine Fondation Sante (Athens, Greece) 2013-01 to 2014-12 | Grant to YA Grant number: YA-Sante Identifying host and microbial factors that promote intestinal inflammation and cancer using Drosophila European Commission (Brussels, Belgium) 2012-05 to 2016-04 | Award to YA Award number: Marie Curie CIG# 303586 Identification of Human Intestinal Bacteria that Promote or Inhibit Inflammation U.S. Department of Defense (DC, DC, United States) 2011-08 to 2012-07 | Award to YA Award number: PR100240 Current Lab Members Popi Georgiades (Postdoctoral Researcher) Stavria Panagidou (PhD Student) Theodoulakis Christofi (PhD Student) Myrofora Panayi (PhD Student) Eleni Kamilari (PhD Student) Savvas Telonis (PhD Student) Amalia Evangelou (MSc thesis) Sofia Kalanidou (MSc thesis) Christina Michail (MSc thesis) Gavriela Sianiou (BSc thesis) Panagiota Gianni (BSC thesis) Alumni Soteroulla Ellina (BSc thesis, 2017) Rafaella Athanasiou (BSc thesis, 2017) Irene Dieronitou (BSc thesis, 2014; MSc thesis, 2016) Amalia Evangelou (BSc thesis, 2016) Sofia Kalanidou (BSc thesis, 2016) Christina Michail (BSc thesis, 2016) Stella Irakleus (BSc thesis, 2016) Styliani Polydorou (BSc thesis, 2016) Alexandros Patapiou (BSc thesis, 2015) Maria Glykenou (BSc thesis, 2015) Maria Michail (BSc thesis, 2015) Kalodoti Avgousti (BSc thesis, 2014) Stelios Theofilou (BSc thesis, 2014) Maria Dimosthenous (BSc thesis, 2014) Panayiota Markou (internship, 2013) Eleni Ioannidou (BSc thesis, 2013) Ilias Tzelepis (BSc thesis, 2013) Stefania Kapsetaki (BSc thesis, 2013) Teaching Genetics BIO-201 (full semester mandatory course) Immunology BIO-471 (full semester mandatory course) Bacterial Pathogenesis BIO-372 (full semester elective course)
Panayidou S, Ioannidou E & Apidianakis Y. Human pathogenic bacteria, fungi and viruses in Drosophila: disease modeling, lessons and shortcomings. Virulence 2014 Jan 7;5(2).
Markou P & Apidianakis Y. Pathogenesis of Pseudomonas aeruginosa infection in patients with cancer. Front Cell Infect Microbiol. 2014 Jan 7;3:115.
Tzelepis I, Kapsetaki SE, Panayidou S & Apidianakis Y. Drosophila melanogaster: a first step and a stepping-stone to anti-infectives. Curr Opin Pharmacol. 2013 Oct;13(5):763-8.