Kapnissi - Christodoulou P. Constantina
Department of Chemistry
Cyprus University of Technology
B.Sc. in Chemistry, University of Cyprus, Nicosia, Cyprus, 1999. Ph.D. in Analytical Chemistry, Louisiana State University, Baton Rouge, Louisiana, USA, 2004. Post-doctoral Research Associate, Rogers NMR Research Center, Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA, 2004-2005. Lecturer, Department of Chemistry, University of Cyprus, 2005-2011. Assistant Professor, Department of Chemistry, University of Cyprus, 2011-2016. Associate Professor, Department of Chemistry, University of Cyprus, 2017-today.
Development of electrophoretic, chromatographic and electrochromatographic methods for improved achiral and chiral separations of various classes of analytes. Use of the hyphenated techniques capillary electrophoresis-mass spectrometry (CE-MS) and ultra-performance liquid chromatography-MS-MS (UPLC-MS-MS) for the separation, detection and quantitation of various classes of analytes. Application of the optimum separation conditions in biological, natural and food samples. Use of enantiomers as diagnostic biomarkers for diseases. Determination of the most effective sample pre-treatment methods. Synthesis, characterization and use of chiral ionic liquids in capillary electrophoresis (CE) for improved separations and better efficiencies. Modification of the capillary columns for improved separations. Evaluation of synergistic enantioseparation systems. Use of cyclofructans as chiral selectors in electrokinetic chromatography (EKC).
Mitrofan, G., Stefan-van Staden, R.-I., Moldoveanu, I., Kapnissi-Christodoulou, C. P. Analysis of L-Thyroxine from Pharmaceutical Formulations Using a Potentio Metricmicrosensor Based on Ionic Liquid, UPB Scientific Bulletin, Series B: Chemistry and Materials Science, 2017, 79, 111-118.
Stavrou, I. J., Agathokleous, E., Kapnissi-Christodoulou, C. P. Chiral selectors in CE-Recent developments and applications (mid 2014-mid 2016), Electrophoresis, 2017, in press.
Papageorgis, P., Polydorou, C., Mpekris, F., Voutouri, C, Agathokleous, E., Kapnissi-Christodoulou, C. P., Stylianopoulos, T. Tranilast-induced stress alleviation in solid tumors improves the efficacy of chemo- and nanotherapeutics in a size-independent manner, Scientific Reports, 2017, in press.