Pekka Mäntsälä
Professor emeritus
Biochemistry
University of Turku
Finland
Biography
Pekka Mäntsälä is working as Professor emeritus in Department of Biochemistry and Food Chemistry, University of Turku. Dr. Mäntsälä research focuses on enzymes involved in the biosynthesis of aromatic polyketide antibiotics in Streptomyces soil bacteria. In collaboration with the Molecular Structural Biology laboratory at Karolinska Institutet, Stockholm, Dr.Mäntsälä have published the structures of 7 enzymes from the anthracycline biosynthetic pathways.
Research Interest
Research is centered around the enzymology of Type II aromatic polyketide biosynthesis in Streptomyces bacteria.
Publications
-
Klika KD, Tähtinen P, Mäntsälä P, Niemi J, Metsä-Ketelä M. The potential of VCD to resolve the epimer vs. inverse epimer quandary. Computational and Theoretical Chemistry. 2012 Jul 15;992:156-63.
-
Claesson M, Siitonen V, Dobritzsch D, Metsäâ€Ketelä M, Schneider G. Crystal structure of the glycosyltransferase SnogD from the biosynthetic pathway of nogalamycin in Streptomyces nogalater. The FEBS journal. 2012 Sep 1;279(17):3251-63.
-
Blauenburg B, Metsä-Ketelä M, Klika KD. Formation of 5-Hydroxy-3-methoxy-1, 4-naphthoquinone and 8-Hydroxy-4-methoxy-1, 2-naphthoquinone from Juglone. ISRN organic chemistry. 2012 Nov 5;2012.
