Philippe Arnaud
Team leader at GReD
Genetique Reproduction & Development
Blaise Pascal University
France
Biography
2012- Team leader at GReD -CNRS Staff scientist (DR2) “ Epigenetic control of cell fate determination” 2004-2011 CNRS Staff scientist (CR)- IGMM UMR5535, Montpellier- Dr. Robert Feil’s team “Role of histone modifications in genomic imprinting”. 2000-2003 Post-Doct (Marie Curie Fellow) - Babraham Institute, Cambridge, UK- GKelsey’s Team "Epigenetic control opf genomic imprinting". 1996-2000 Ph.D – Université Blaise Pascal, Clermont-Ferrand.J.M Deragon’s Team "DNA methylation and Host defence hypothesis: The plant SINE S1Bn as a model".
Research Interest
Genomic Imprinting and the epigenetic control of cell fate determination
Publications
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S. Maupetit-Mehouas, B. Montibus, D. Nury, C. Tayama, M. Wassef, S. Kota, A. Fogli, F. Cerqueira Campos, K. Hata, R. Feil, R. Magueron, K. Nakabayashi, F. Court and P. Arnaud, “Imprinting control regions (ICRs) are marked by mono-allelic bivalent chromatin when transcriptionally inactive.â€, Nucleic Acids Res., vol. 44 (2) , pp. 621-635, 2016.
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T. Bouschet, E. Dubois, C. Reynes, S. Kota, S. Rialle, S. Maupetit-Mehouas, M. Pezet, A. Le Digarcher, S. Nidelet, V. Demolombe, P. Cavelier, C. Meusnier, C. Maurizy, R. Sabatier, R. Feil, P. Arnaud, L. Journot and A. Varrault, “In Vitro Corticogenesis from Embryonic Stem Cells Recapitulates the In Vivo Epigenetic Control of Imprinted Gene Expression.â€, Cerebral cortex (New York, N.Y. : 1991), 2016.
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F. Court and P. Arnaud, “An annotated list of bivalent chromatin regions in human ES cells: a new tool for cancer epigenetic research.â€, Oncotarget, vol. 8 (3) , pp. 4110–4124, 2017.
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A. Fogli, M. Demattei, L. Corset, C. Vaurs-Barriere, E. Chautard, J. Biau, J. Kemeny, C. Godfraind, B. Pereira, T. Khalil, N. Grandin, P. Arnaud, M. Charbonneau and P. Verrelle, “Detection of the alternative lengthening of telomeres pathway in malignant gliomas for improved molecular diagnosis.â€, Journal of neuro-oncology, 2017.
