Bruno Bontempi

Biography

 Research themes (FENS): Cognition and behavior / Cognition and behavior of animals; Neurological and psychiatric conditions / Developmental disorders; Neurological and psychiatric conditions / Psychiatric disorders; Cognition and Behavior / Human Cognition and Behavior Scientific Expertise: memory processes; hippocampo-cortical interactions; cholinergic system; glutamatergic system; cell and molecular biology; hippocampal neurogenesis; animal models of Alzheimer's disease; animal models of schizophrenia Technological expertise: fIRM - Magnetic Resonance Brain Functional Imaging; Quantum radiography; virtual reality  395. Erwan Bezard Research interests: Normal and pathological motor skills Normal and pathological cognition Neuropsychopharmacology and therapeutics of deficits - transverse axis Research topics (FENS): Neurological and psychiatric conditions / Neurodegenerative pathologies; Motor System / Basal ganglia; Synaptic transmission and excitability / receptors coupled to G proteins; Cognition and behavior / Animal cognition and behaviour.          Research projects:     Using multidisciplinary approaches combining functional anatomy, biochemistry and molecular biology, we try to understand the mechanisms responsible for the hypokinesis characteristic of parkinsonian syndromes, its response to L-Dopa and its complications such as Dopa- (DDI), as well as the mechanisms leading to neuronal death in these pathologies. Our work calls for the analysis of the behavior of rodents, nonhuman primates and human brain (human cerebrothèque) in order to establish correlations. Using mainly gene transfer or human brain purification, we then modulate the severity of the symptoms or the degree of neuronal death in order to establish a causal link.

Research Interest

 Neurology