Thomas Boraud

Biography

Research themes: Normal and pathological cognition Research Themes (FENS): Cognition and behavior / Motivation and emotion; Neurological and psychiatric conditions / Neurodegenerative diseases; Motor System / Basal Ganglia Scientific Expertise: In vivo electrophysiology; pre-clinical expertise; Parkinson disease ; animal models; integrated neurophysiology; pharmacology; Neurocomputation; dopamine; modelization ; development Research:            The paradox of the basal ganglia (GB) is that the clinical expression of their dysregulation is well characterized, in particular as regards the motor pathologies; on the other hand, their functional roles are still badly determined. The main reason for this is the great complexity of the system. This complexity is both structural, because the network is made up of many interconnected and functional units, because the system intervenes in integrative functions at the boundary of the motor, cognitive and mood regulation. To solve this problem, he studies the role of the dorsal part in the motivated behavior, which he approaches from different angles and through various collaborations. To address structural complexity, he draw inspiration from the systemic analysis that consists of i) (ii) to establish the possible stable states of the system and (iii) to reason with the objective of the system. In this framework I associate modeling and electrophysiological approach multi-channel-multi-sites in rodent and primate to characterize the extrapyramidal network and its function.  

Research Interest

 Neurology