Vitale Nicolas

Biography

SCIENTIFIC CURSUS - From 2010: Editor Scientific Reports  -  From 2006: DR2 INSERM. Editorial Board member of the Journal of Biological Chemistry, Frontiers in Neuroendocrine Sciences and Current Chemical Biology. - 2003 : HRD Université Louis Pasteur de Strasbourg. - 1997 : CR2 INSERM at the U-338 INSERM (Dir. Dominique Aunis) - 1997-1995 : postdoctoral position in the Pulmonary-Critical Care Medicine Branch, National Heart, Lung and Blood Institute of the National Institute of Health à Bethesda (Dir. Joel Moss). Fellowship INSERM, then Fogarty. - 1994-1992 : PhD under the supervision of Marie-France Bader. Teaching at the Faculty of Medicine of Strasbourg. Scientific summary   Cells control very precisely their three-dimensional organization and to do so, they have developed specialized subcellular compartments. For instance, vesicular structures assure the transport of specific molecules from one part of the cell to another. To maintain cellular homeostasis, the distribution and composition of these structures are very tightly regulated. Hence, most cellular activities including cell communication, defense and migration involve vesicular trafficking steps, which end by the fusion of distinct membrane compartments. Despite a fundamental mechanism that appears very similar (i.e. the fusion between two lipid bi-layers), the kinetics and spatial and temporal regulation of these different processes vary greatly (from milliseconds for neurotransmitter release to minutes for phagocytosis), arguing for essential differences in the underlying mechanisms.

Research Interest

Neurology