Patrick Schultz
Department director
Integrated Structural Biology
IGBMC
France
Biography
Patrick Schultz gained a background in molecular biology and genetics at the University Louis Pasteur and pursued his academic career by a thesis on chromatin organization under the direction of P. Oudet (1987). After an internship at EMBL, he started a post-doctoral fellowship at LGME (Strasbourg) and oriented his research towards the structural investigation of molecular complexes involved in transcription. In 1991, he determined the first three-dimensional model of RNA polymerase I by electron microscopy. He joined the newly created IGBMC in 1994 to solve the molecular organization of general transcription factors (TFIIH, TFIIE, and TFIID) as well as of co-activators (TFIID and SAGA). Since then, he works on a better understanding of the structure and the assembly modes of transcription initiation complexes and on the mechanisms of regulatory signal transduction.
Research Interest
structural investigation of molecular complexes involved in transcription.
