Patrick Schultz
Molecular Biology
Institute of Genetics and Molecular and Cellular Biology: IGBMC.
France
Biography
Patrick Schultz gained a background in molecular biology and genetics at the University Louis Pasteur and pursued his academic career by a thesis on chromatin organization under the direction of P. Oudet (1987). After an internship at EMBL, he started a post-doctoral fellowship at LGME (Strasbourg) and oriented his research towards the structural investigation of molecular complexes involved in transcription. In 1991, he determined the first three-dimensional model of RNA polymerase I by electron microscopy. He joined the newly created IGBMC in 1994 to solve the molecular organization of general transcription factors (TFIIH, TFIIE, and TFIID) as well as of co-activators (TFIID and SAGA). Since then, he works on a better understanding of the structure and the assembly modes of transcription initiation complexes and on the mechanisms of regulatory signal transduction.
Research Interest
Molecular Biology,Cell Biology,Genome Biology
