Matilde Cordero-erausquin
Neurology
The European Neuroscience Institute in Paris, Pasteur
France
Biography
She is neurologist and working on chronic pain is a devastating and widespread problem yet the existing treatments have limited long-term efficacy. Their research focuses on spinal cholinergic analgesia as a source of alternative therapy. Spinal acetylcholine (ACh) is an important modulator of sensory processing, also implicated in the analgesic effects of clonidine and morphine. Their latest results have demonstrated that this ACh arises from a sparse population of dorsal horn cholinergic interneurons. Understanding how such a sparse population achieves a major control of nociceptive processing is an ambitious challenges that their address using a combination of neuroanatomy, behavioural experiments, electrophysiology and optogenetics.
Research Interest
Neurology
