Dennis W. Wolan
Professor
Molecular Medicine
The Scripps Research University
France
Biography
Department of Chemical Physiology,Faculty, Graduate Program-Professor, Ph.D., Biology, University of California, Santa Barbara, Ray Thomas Edwards Foundation Recognition Award Ruth L. Kirschstein NCI/NIH Postdoctoral Fellowship, Skaggs Pre-doctoral Fellowship National Science Foundation Pre-doctoral Fellowship ,Member of the American Chemical and International Proteolysis Societies.
Research Interest
Focused to design small molecule modulators of protein function as novel foundations for therapeutics and as tools for elucidating functional roles of enzymes in biological processes.
Publications
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Backus, K.M., Correia, B.E., Lum, K.M., Forli, S., Horning, B.D., González-Páez, G.E., Chatterjee, S., Lanning, B.R., Teijaro, J.R., Olson, A.J., Wolan, D.W. and Cravatt, B.F. 2016. “Proteome-wide covalent ligand discovery in native biological systems.†Nature. 534, 570-574.
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Chatterjee, S., Stupp, G.S., Park, S.K., Ducom, J.-C., Yates III, J.R., Su, A.I. and Wolan, D.W. 2016. “A comprehensive and scalable database search system for metaproteomics.†BMC Genomics. 17, 642.
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Mayers, M.D., Moon, C., Stupp, G.S., Su, A.I. and Wolan, D.W. 2017. “Quantitative metaproteomics and activity-based probe enrichment reveals significant alterations in protein expression from a mouse model of inflammatory bowel disease.†J. Proteome Res. online
