Derek Duckett
Scientific Director
Molecular Medicine
The Scripps Research University
France
Biography
Ph.D. (Biochemistry), The University of Dundee , Professor of Molecular Therapeutics, Molecular Therapeutics, The Scripps Research Institute and scientific directors.Editorial board member and won many honours and awards like Member, American Association for Cancer Research.
Research Interest
Mainly focused to design novel drug and therapeutics based on oncology and tumor suppressor.
Publications
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Development of highly selective casein kinase 1δ/1ε (CK1δ/ε) inhibitors with potent antiproliferative properties. Bibian M, Rahaim RJ, Choi JY, Noguchi Y, Schürer S, Chen W, Nakanishi S, Licht K, Rosenberg LH, Li L, Feng Y, Cameron MD, Duckett DR, Cleveland JL, Roush WR. Bioorg Med Chem Lett. 2013 Aug 1;23(15):4374-80. doi: 10.1016/j.bmcl.2013.05.075. Epub 2013 May 31. PMID: 23787102
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Identification of an EGFRvIII-JNK2-HGF/c-Met-Signaling Axis Required for Intercellular Crosstalk and Glioblastoma Multiforme Cell Invasion. Saunders VC, Lafitte M, Adrados I, Quereda V, Feurstein D, Ling Y, Fallahi M, Rosenberg LH, Duckett DR. Mol Pharmacol. 2015 Dec;88(6):962-9. doi: 10.1124/mol.115.097774. Epub 2015 Oct 9. PMID: 26452771
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Therapeutic targeting of casein kinase 1δ in breast cancer. Rosenberg LH, Lafitte M, Quereda V, Grant W, Chen W, Bibian M, Noguchi Y, Fallahi M, Yang C, Chang JC, Roush WR, Cleveland JL, Duckett DR. Sci Transl Med. 2015 Dec 16;7(318):318ra202. doi: 10.1126/scitranslmed.aac8773. PMID: 26676609
