Michael Zwick
Professor
Molecular Medicine
The Scripps Research University
France
Biography
Faculty, Graduate Program, Professor-Department of Immunology and Microbiology . Ph.D., Molecular Biology, Simon Fraser University, awards like Elizabeth Glaser Pediatric AIDS Foundation Scholarship Award; 07/01 - IAS Young Investigator Award (Travel Scholarship); 01/00 to 12/01 - Natural Sciences and Engineering Research Council of Canada Post-doctoral Fellowship (NSERC PDF); 09/98 - 12/98 Graduate Fellowship (SFU) 05/96 - 05/98 NSERC Post Graduate Scholarship (PGS B) 05/94 - 05/96 NSERC PGS A 05/92 - 08/92 Faculty of Medicine Summer Student Research Scholarship.
Research Interest
Mainly focused in studying HIV-AIDS work on the diseases and design antibiotics making the immunity stronger specially in this diseases.We study neutralizing epitopes on the ectodomain of gp41 that are proximal to the membrane-spanning domain as well as those that become transiently exposed during fusion. We also immunize animals with engineered immunogens in an effort to elicit HIV neutralizing antibodies.
Publications
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Kim AS, Leaman DP & Zwick MB (2014) Antibody to gp41 MPER alters functional properties of HIV-1 Env without complete neutralization. PLoS Pathog. 10(7):e1004271.
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Leaman DP, Lee JH, Ward AB & Zwick MB (2015) Immunogenic display of purified chemically cross-linked HIV-1 spikes. J Virol. 89(13):6725-45.
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Ingale J, Stano A, Guenaga J, Sharma SK, Nemazee D, Zwick MB & Wyatt RT (2016) High-density array of well-ordered HIV-1 spikes on synthetic liposomal nanoparticles efficiently activate B cells. Cell Rep. 15(9):1986-1999.
