Shane Crotty
Professor
Immunology and Microbiology
The Scripps Research University
France
Biography
Ph.D. (Biochemistry and Molecular Biology), University of California, San Francisco.Professor,Immunology and Microbial Science (IMS), The Scripps Research Institute. Associate Professor, La Jolla Institute for Allergy and Immunology.
Research Interest
Reseach focus is mainly for designing immune therapeuutics against immune diseases.
Publications
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Havenar-Daughton, C., Carnathan, D. G., Torrents de la Peña, A., Pauthner, M., Briney, B., Reiss, S. M., Wood, J. S., Kaushik, K., van Gils, M. J., Rosales, S. L., van der Woude, P., Locci, M., et al. Direct probing of germinal center responses reveals immunological features and bottlenecks for neutralizing antibody responses to HIV Env trimer. (2016). Cell Reports, 17(9), 2195-2209. PMCID: PMC5142765.
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Havenar-Daughton, C., Lee, J. H. & Crotty, S. Tfh cells and HIV bnAbs, an immunodominance model of the HIV neutralizing antibody generation problem. (2017). Immunological Reviews, 275(1), 49-61.
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Pauthner, M., Havenar-Daughton, C., Sok, D., Nkolola, J. P., Bastidas, R., Boopathy, A. V., Carnathan, D. G., Chandrashekar, A., Cirelli, K. M., Cottrell, C. A., Eroshkin, A. M., Guenaga, J., et al. Elicitation of robust tier 2 neutralizing antibody responses in nonhuman primates by HIV envelope trimer immunization using optimized approaches. (2017). Immunity, 46(6), 1073-1088. PMCID: PMC5483234.