Christoph Michel

Biography

 In his lab, we use animal models to better understand the cellular and molecular mechanisms of neuronal network functions and their pathologies. Animal models are complementary to the human studies because they allow for invasive electrophysiological recordings and for manipulations of brain activities that are not possible in the clinic. They notably developed simultaneous surface EEG and intracerebral recordings in the awake rodent and they combine these recordings with optogenetic excitation and inhibition of specific neuronal populations. Using this approach they can dissect the network mechanisms by which local and large-scale neuronal networks are integrated and how these processes are altered in models of brain disorders such as neonatal lesions, psychiatric diseases and epilepsy.

Research Interest

 Neurology