David K. Meyerholz
Director
Division of Comparative Pathology
University of Iowa Health care
France
Biography
Education DVM, Iowa State University MS, Iowa State University PhD, Iowa State University Resident, Veterinary Pathology, Iowa State University Licensure and Certifications Diplomate - American College of Veterinary Microbiologists (Virology) Diplomate - American College of Veterinary Pathologists Center, Program and Institute Affiliations Center for Gene Therapy of Cystic Fibrosis and other Genetic Diseases, Center for Immunology and Immune-based Diseases, Cystic Fibrosis Research Center, Institute for Clinical and Translational Science
Research Interest
Dr. Meyerholz studies cystic fibrosis (CF), a genetic condition cause by mutations in CFTR gene. Goals of his research are to define the molecular origins of CF disease, identify new biomarkers and evaluate novel treatments. He also has research interests in diseases of the lung (e.g. influenza, MERS-CoV, RSV, SARS-CoV) as well as comparative pathology, cardiovascular disease, cancer and neurofibromatosis-1. Dr. Meyerholz has published >155 peer-reviewed papers in scientific journals.
Publications
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Meyerholz, D. K., Lambertz, A. M., Reznikov, L. R., Ofori-Amanfo, G. K., Karp, P. H., McCray, Jr, P. B., Welsh, M. J. & Stoltz, D. A. (2016). Immunohistochemical Detection of Markers for Translational Studies of Lung Disease in Pigs and Humans. Toxicologic pathology, 44(3), 434-41. PMID: 26511846.
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Channappanavar, R., Fehr, A. R., Vijay, R., Mack, M., Zhao, J., Meyerholz, D. K. & Perlman, S. (2016). Dysregulated Type I Interferon and Inflammatory Monocyte-Macrophage Responses Cause Lethal Pneumonia in SARS-CoV-Infected Mice. Cell host & microbe, 19(2), 181-93. PMID: 26867177.
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Shah, V. S., Meyerholz, D. K., Tang, X. X., Reznikov, L., Abou Alaiwa, M., Ernst, S. E., Karp, P. H., Wohlford-Lenane, C. L., Heilmann, K. P., Leidinger, M. R., Allen, P. D., Zabner, J., McCray, Jr, P. B., Ostedgaard, L. S., Stoltz, D. A., Randak, C. O. & Welsh, M. J. (2016). Airway acidification initiates host defense abnormalities in cystic fibrosis mice. Science (New York, N.Y.), 351(6272), 503-7. PMID: 26823428.
