Eric R. Fearon, Md, Phd

Biography

 Since 1995, Dr. Eric Fearon has served as the Maisel Professor of Oncology and as Associate Director for Basic Research at the University of Michigan Comprehensive Cancer Center (UMCCC). He was named Deputy Director of the UMCCC in 2005 and he holds the title of Professor in the Departments of Internal Medicine, Human Genetics, and Pathology at the University of Michigan Medical School. In 2010 Dr. Fearon was appointed as the Division Chief for the Molecular Medicine and Genetics Division in the Department of Internal Medicine.  Dr. Fearon has authored more than 130 peer-reviewed research manuscripts and more than 60 review/editorial articles and book chapters. He and his laboratory have pursued research in the cancer genetics field, particularly investigations of the multiple gene defects that underlie colorectal tumor development and progression. Current topics of investigation include studies of the Wnt/beta-catenin/TCF, CDX2, p53, and E-cadherin pathways in normal and neoplastic tissues.  Dr. Fearon has served on the editorial boards of various journals in the cancer biology and human genetics fields and currently is an editorial board member or editor at 10 journals. In addition, he has served as a member or chair of various National Institutes of Health (NIH) advisory groups and grant review committees.

Research Interest

 The research in the Fearon laboratory seeks to address the means by which specific oncogene and tumor suppressor gene defects contribute to the pathogenesis of colon and other cancers and to develop novel strategies for early detection and treatment of colorectal adenomas and carcinomas.