University of Paris
Jacques Hugon Professor MD PhD Neurologist at Lariboisiere Hospital Centre Memoir (CMRR) at University of Paris. Chair, Professor, Head of the Department at University of Hong Kong. A team from Lariboisiere Hospital, led by Pr Hugon in Paris France has just revealed that a potent killer enzyme, PKR, was activated in the brain and cerebrospinal fluid (CSF) of AD patients. This team has found that the level of activated PKR was three time higher in the CSF of AD patients as compared to controls. New researches are underway to attenuate its functions by new specific “kinase inhibitors” that could represent a powerful way to attenuate memory deficits in AD patients.