Christoph Bräuchle

Biography

Postdoc Fellowship IBM San José (California) USA; Teaching und Research Assistant LMU München; C2-Assistant Professor LMU München

Research Interest

Spectroscopy, Imaging and Manipulation of Single Molecules and Nanoparticles in Bio- and Nano-Sciences; Dynamics of single molecules in nanoporous systems: mechanistical studies of translation, rotation, adsorption and spectral diffusion of single molecules in mesoporous silica structures and other nanoporous systems; Development of smart drug delivery systems/nanomedicine: drug delivery with mesoporous silica nanoparticles, polyplexes and lipoplexes/targeting, controlled release and depot effect, live cell imaging of uptake and trafficking in living cells; Live cell imaging and single virus tracing: observation of the infection pathway of a single virus into a living cell and production (self-assembly and budding) of viruses in infected cells for HIV and Herpes; Nanoparticles and human health: live cell imaging of uptake and trafficking of nanoparticles (SiO2, TiO2, ZnO, CeO, Pt etc.) in endothelial cells in an artificial blood circulation model and toxicity measurements; Hybrid nanosystems for light collection: combination of light harvesting complexes (photosynthesis) with metal nanoparticles (plasmons) as advanced biomimetic systems for solar energy collection; Force spectroscopy with single polymer chains, especially polysiloxanes