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Genetics Experts

Thomas Carell

Professor
Carell Group
Center for NanoScience
Germany

Biography

Thomas Carell was born in Herford (Germany) in 1966. He is married and father of three children. His academic career in chemistry began at the Universities of Münster and Heidelberg. In 1993 he obtained his doctorate with Prof. H. A. Staab at the Max Planck Institute of Medical Research. After postdoctoral training with Prof. J. Rebek at MIT (Cambridge, USA) in 1993-1995, Thomas Carell moved to the ETH Zürich (Switzerland) into the group of Prof. F. Diederich to start independent research. He obtained his habilitation in 1999. In 2000 he accepted a full professor position for Organic Chemistry at the Philipps-Universität in Marburg (Germany). In 2004 he moved to the Ludwig-Maximilians-Universität (LMU) in Munich (Germany) where he is heading a research group in chemical biology focused to analyze the chemistry of epigenetic programming in DNA and RNA. Thomas Carell is a member of the German National Academy Leopoldina and of the Berlin-Brandenburgische Academy of Arts and Sciences. He is the recipient of the Cross of Merit from the Federal Republic of Germany.

Research Interest

Genetic system

Publications

  • Thienpont, J. Steinbacher, H. Zhao, F. D'Anna, A. Kuchnio, A. Ploumakis, B. Ghesquière, L. Van Dyck, B. Boeckx, L. Schoonjans, E. Hermans, F. Amant, V. N. Kristensen, K. P. Koh, M. Mazzone, M. L. Coleman, T. Carell, P. Carmeliet, D. Lambrechts Nature, 2016, doi: 10.1038/nature19081 Tumour hypoxia causes DNA hypermethylation by reducing TET activity.

  • R. Rahimoff, O. Kosmatchev, A. Kirchner, T. Pfaffeneder, F. Spada, V. Brantl, M Müller, T. Carell J. Am. Chem. Soc, 2017, doi:10.1021/jacs.7b04131

  • R. R. Edupuganti, S. Geiger, R. G. H. Lindeboom, H. Shi, P. J. Hsu, Z. Lu, S.-Y. Wang, M. P. A. Baltissen, P. W. T. C. Jansen, M. Rossa, M. Müller, H. G. Stunnenberg, C. He*, T. Carell*, M. Vermeulen* Nat. Struct. Mol. Biol., 2017, doi:10.1038/nsmb.3462

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